Immune system
Recent articles
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.
Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Atlas charts cells of human placenta, uterus across early pregnancy
A new resource gives an unparalleled look at how fetal placental cells attach to the uterine wall and remodel maternal blood vessels to access nutrients.
Atlas charts cells of human placenta, uterus across early pregnancy
A new resource gives an unparalleled look at how fetal placental cells attach to the uterine wall and remodel maternal blood vessels to access nutrients.
‘wildDISCO’ cocktail yields whole-body maps of mouse neurons and more
A new technique used to create see-through rodents can help scientists analyze how the nervous system interacts with other body systems.
‘wildDISCO’ cocktail yields whole-body maps of mouse neurons and more
A new technique used to create see-through rodents can help scientists analyze how the nervous system interacts with other body systems.
Serotonin powers pruning of developing brain circuits in mice
Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.
Serotonin powers pruning of developing brain circuits in mice
Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.
Maternal immune response dulls male rats’ social radar
Male rats prenatally exposed to a maternal immune response have atypical responses to other rats in distress, according to a new study.
Maternal immune response dulls male rats’ social radar
Male rats prenatally exposed to a maternal immune response have atypical responses to other rats in distress, according to a new study.
Null and Noteworthy: Registered reports; motor measurements; viral DNA
In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results.
Null and Noteworthy: Registered reports; motor measurements; viral DNA
In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results.
Immunity-linked genes expressed differently in brains of autistic people
Postmortem brain samples from people with one of six conditions, including autism, show distinct signatures of over- and underexpression of immune genes.
Immunity-linked genes expressed differently in brains of autistic people
Postmortem brain samples from people with one of six conditions, including autism, show distinct signatures of over- and underexpression of immune genes.
Explore more from The Transmitter
Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.
Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.
Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.
Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.
Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.
Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.