Glymphatic system

Recent articles

Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read
Illustration of a lab with a smoking crater in the middle of the floor.

The Transmitter’s favorite features of 2024

Our chosen stories include tales about research misconduct in the lab, a neuroscientist working at the end of the world, and the passing of neuroanatomy’s “great-grandfather,” Harvey Karten.

By The Transmitter
23 December 2024 | 2 min read
New method reignites controversy over brain clearance during sleep.

New method reignites controversy over brain clearance during sleep

Tracers injected directly into mouse brain tissue instead of the cerebrospinal fluid show that brain clearance slows during sleep and under anesthesia, according to a study published last week—but proponents of the glymphatic system theory take issue with the technique.

By Elissa Welle
22 May 2024 | 7 min read
Maiken Nedergaard, Britta Engelhardt and Christer Betsholtz on a floating rock island with university facilities and abstract shapes.

Maiken Nedergaard’s power of disruption

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

By Emily Sohn
26 February 2024 | 26 min listen

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Research image of brain organoids with astroglia formation represented in green.

Personalized medicine; astroglia organoids; fast track for fragile X drug

Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.

By Jill Adams
21 January 2025 | 2 min read
Illustration of clinicians, a pill bottle, a speech bubble and shadowy figures.

Neuroscientists need to do better at explaining basic mental health research

The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.

By Omar Abubaker, Karla Kaun, Eric J. Nestler
21 January 2025 | 7 min read
Grid of human brain scans.

Dose, scan, repeat: Tracking the neurological effects of oral contraceptives

We know little about how the brain responds to oral contraceptives, despite their widespread use. I am committed to changing that: I scanned my brain 75 times over the course of a year and plan to make my data openly available.

By Carina Heller
20 January 2025 | 7 min read