Glymphatic system

Recent articles

Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read
Illustration of a lab with a smoking crater in the middle of the floor.

The Transmitter’s favorite features of 2024

Our chosen stories include tales about research misconduct in the lab, a neuroscientist working at the end of the world, and the passing of neuroanatomy’s “great-grandfather,” Harvey Karten.

By The Transmitter
23 December 2024 | 2 min read
New method reignites controversy over brain clearance during sleep.

New method reignites controversy over brain clearance during sleep

Tracers injected directly into mouse brain tissue instead of the cerebrospinal fluid show that brain clearance slows during sleep and under anesthesia, according to a study published last week—but proponents of the glymphatic system theory take issue with the technique.

By Elissa Welle
22 May 2024 | 8 min read
Maiken Nedergaard, Britta Engelhardt and Christer Betsholtz on a floating rock island with university facilities and abstract shapes.

Maiken Nedergaard’s power of disruption

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

By Emily Sohn
26 February 2024 | 26 min listen

Explore more from The Transmitter

Colorful drawing of a human brain.

‘Neuroethics: The Implications of Mapping and Changing the Brain,’ an excerpt

In his new book, published today, philosopher Walter Glannon examines the ethics of six areas of neuroscience. In Chapter 4, a portion of which appears below, he tackles the ethical considerations of using brain organoids in research.

By Walter Glannon
11 November 2025 | 7 min read
Human brain cross-sections.

Teasing out mosaicism cell by cell; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 10 November.

By Jill Adams
11 November 2025 | 2 min read
A monkey brain slice.

Without monkeys, neuroscience has no future

Research in primate brains has been essential for the development of brain-computer interfaces and artificial neural networks. New funding and policy changes put the future of such advances at risk.

By Cory Miller, J. Anthony Movshon, Doris Tsao
10 November 2025 | 5 min read

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