Glymphatic system

Recent articles

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch
fMRI scans showing the movement of cerebrospinal fluid.

Noninvasive method lifts curtain on cerebrospinal-fluid dance in human brain

Cerebrospinal fluid shows brain-region-specific dynamics, a new high-resolution MRI approach reveals.

By Claudia López Lloreda
14 November 2025 | 4 min read
Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read
Illustration of a lab with a smoking crater in the middle of the floor.

The Transmitter’s favorite features of 2024

Our chosen stories include tales about research misconduct in the lab, a neuroscientist working at the end of the world, and the passing of neuroanatomy’s “great-grandfather,” Harvey Karten.

By The Transmitter
23 December 2024 | 2 min read
New method reignites controversy over brain clearance during sleep.

New method reignites controversy over brain clearance during sleep

Tracers injected directly into mouse brain tissue instead of the cerebrospinal fluid show that brain clearance slows during sleep and under anesthesia, according to a study published last week—but proponents of the glymphatic system theory take issue with the technique.

By Elissa Welle
22 May 2024 | 8 min read
Maiken Nedergaard, Britta Engelhardt and Christer Betsholtz on a floating rock island with university facilities and abstract shapes.

Maiken Nedergaard’s power of disruption

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

By Emily Sohn
26 February 2024 | 24 min read

Explore more from The Transmitter

Mice playing, engaged in learning and memory: some of their brains are yellow, and some are red, matching a red and yellow legend that runs through the image to underscore both memory and learning.

This paper changed my life: A technical breakthrough for memory studies

In a 2007 Science paper, Mark Mayford and his colleagues found that some neurons activated during learning are also recruited during memory retrieval. Noelia Weisstaub shares how this study and others drove an era of great progress in tool development.

By Noelia Weisstaub
14 August 2026 | 5 min read

Early experience reshapes zebrafish retinal cells, alters behavior

The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.

By Siddhant Pusdekar
13 August 2026 | 0 min watch
Research image of expression of MEIS2 in PV interneurons.

Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions

Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.

By Claudia López Lloreda
12 August 2026 | 5 min read