Glymphatic system

Recent articles

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch
fMRI scans showing the movement of cerebrospinal fluid.

Noninvasive method lifts curtain on cerebrospinal-fluid dance in human brain

Cerebrospinal fluid shows brain-region-specific dynamics, a new high-resolution MRI approach reveals.

By Claudia López Lloreda
14 November 2025 | 4 min read
Three sleeping mice.

Fleeting sleep interruptions may help brain reset

Brief, seconds-long microarousals during deep sleep “ride on the wave” of locus coeruleus activity in mice and correlate with periods of waste clearing and memory consolidation, new research suggests.

By Shaena Montanari
13 January 2025 | 5 min read
Illustration of a lab with a smoking crater in the middle of the floor.

The Transmitter’s favorite features of 2024

Our chosen stories include tales about research misconduct in the lab, a neuroscientist working at the end of the world, and the passing of neuroanatomy’s “great-grandfather,” Harvey Karten.

By The Transmitter
23 December 2024 | 2 min read
New method reignites controversy over brain clearance during sleep.

New method reignites controversy over brain clearance during sleep

Tracers injected directly into mouse brain tissue instead of the cerebrospinal fluid show that brain clearance slows during sleep and under anesthesia, according to a study published last week—but proponents of the glymphatic system theory take issue with the technique.

By Elissa Welle
22 May 2024 | 8 min read
Maiken Nedergaard, Britta Engelhardt and Christer Betsholtz on a floating rock island with university facilities and abstract shapes.

Maiken Nedergaard’s power of disruption

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

By Emily Sohn
26 February 2024 | 24 min read

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Barbara Finlay looking at a glass jar with a brain.

Remembering Barbara Finlay, ‘maverick’ of evolutionary neuroscience

Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains, a concept she used to model the timing of hundreds of events and align them across mammalian species.

By Calli McMurray
23 October 2026 | 8 min read
A crow looking at a screen showing a circle of white dots on a black background.

Crows have brains ‘in the fast lane’

The birds accurately complete decision-making tasks twice as fast as primates, although their endbrains look considerably different.

By Sarah Thau
22 October 2026 | 4 min read
A boy manipulates blocks at a table while sitting across from a woman taking notes.

Prevalence of profound autism declines with new definition

The updated, more precise definition used in a CDC study includes adaptive scores.

By Brianna Abbott
22 October 2026 | 5 min read