Gene networks
Recent articles
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Autism-linked proteins mingle with other molecules in overlapping networks
A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.
Autism-linked proteins mingle with other molecules in overlapping networks
A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Two top autism-linked proteins connect to build cell ‘skeleton’
ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.
Two top autism-linked proteins connect to build cell ‘skeleton’
ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.
Autism and the complete human genome: Q&A with Evan Eichler
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
Autism and the complete human genome: Q&A with Evan Eichler
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Differing gene functions across species may pose problems for autism models
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
Differing gene functions across species may pose problems for autism models
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
Proteome map identifies more than 90 percent of all human proteins
Researchers expand on the already enormous progress made on the Human Proteome Project
Proteome map identifies more than 90 percent of all human proteins
Researchers expand on the already enormous progress made on the Human Proteome Project
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Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
Cell population in brainstem coordinates cough, new study shows
The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.
In updated U.S. autism bill, Congress calls for funding boost, expanded scope
The current Autism CARES Act sunsets in late September.
In updated U.S. autism bill, Congress calls for funding boost, expanded scope
The current Autism CARES Act sunsets in late September.
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.