Gene networks
Recent articles
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Newfound gene network controls long-range connections between emotional, cognitive brain areas
The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Autism-linked proteins mingle with other molecules in overlapping networks
A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.
Autism-linked proteins mingle with other molecules in overlapping networks
A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Two top autism-linked proteins connect to build cell ‘skeleton’
ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.
Two top autism-linked proteins connect to build cell ‘skeleton’
ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.
Autism and the complete human genome: Q&A with Evan Eichler
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
Autism and the complete human genome: Q&A with Evan Eichler
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Autism genetics, explained
The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.
Explore more from The Transmitter
Functional MRI can do more than you think
Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.
Functional MRI can do more than you think
Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.
As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap
Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.
As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap
Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.