Fragile X syndrome

Recent articles

Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read
An opaque cube is repeated multiple times to create the appearance of overlapping cubes.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read
Dendritic spine images.

Targeting NMDA receptor subunit reverses fragile X traits in mice

The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.

By Angie Voyles Askham
6 March 2025 | 5 min read
A research image of X chromosomes with Fragile X syndrome

Understanding fragile X syndrome

Just in time for Fragile X Awareness Month, The Transmitter rounds up notable coverage.

By Daisy Yuhas
4 July 2024 | 2 min read
Two hands hold a mouse.

Noisy brain may underlie some of autism’s sensory features

Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.

By Holly Barker
18 January 2024 | 6 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
Two mice touching.

‘Social touch’ responses in mice gauged with unprecedented control

A new tool could help decipher the brain circuits underlying aversion to social touch, which is common in people with autism.

By Celia Ford
19 September 2023 | 4 min read
Research image of neurons in mice.

Skewed signaling in striatum may spawn repetitive behaviors

Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.

By Holly Barker
6 September 2023 | 3 min read
Research images of protein synthesis in mice.

Neuronal deafness to stress may add to protein surplus in fragile X

A protective pathway that pauses protein synthesis is muted in a mouse model of fragile X syndrome, according to a new study.

By Holly Barker
29 August 2023 | 3 min read
A grid of four brain scans showing excess cerebrospinal fluid.

Is excess brain fluid an early marker of autism?

Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.

By Giorgia Guglielmi
17 August 2023 | 9 min read

Explore more from The Transmitter

Illustration of pipa frog showing nerves in fingertips.

How the pipa frog hunts prey by touch

Each of the frog’s eight fingers branches into 16 ultra-sensitive tips, which together function as a fovea—potentially the first demonstration of this type of sensory structure outside of mammals.

By Calli McMurray
30 September 2026 | 7 min read
scaled

Response to ‘Finally, a new route for the magnetic-sense field’

Magnetoreception in Drosophila has much to offer those with an interest in neuroscience.

By Denis Henshaw
30 September 2026 | 3 min read
Research image of perineuronal nets.

Organoids missing the TSC2 gene form rogue astrocytes; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 September.

By Jill Adams
29 September 2026 | 2 min read