Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Susumu Tonegawa.

In memoriam: Susumu Tonegawa, ‘intellectual giant’

He won the Nobel Prize for his work on immunology and then went on to define the field of learning and memory.

By Claudia López Lloreda
17 July 2026 | 6 min read
Research image of mouse and human Purkinje cells.

Purkinje cells evolved to have increasingly complex architecture

An increasing proportion of the cerebellar neurons acquired multiple primary dendrites in humans and other apes, according to a comparison of 11 primate species.

By Siddhant Pusdekar
16 July 2026 | 5 min read