Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Curvy lines link brain scans and a world map.

BRAIN Initiative researchers ‘dream big’ amid shifts in leadership, funding

But whether the initiative’s road map for the next decade is feasible remains an open question.

By Claudia López Lloreda
23 January 2026 | 6 min read
Two piggy banks whose slots form a plus symbol and a minus symbol.

Neuroscience, BRAIN Initiative gain budget in ‘bad’ NIH funding bill

The bill goes before the House of Representatives today and outlines increases for neuroscience-related research—including a 33 percent increase to the BRAIN Initiative—but maintains a multiyear spending approach that could limit the number of grants awarded overall.

By Angie Voyles Askham
22 January 2026 | 4 min read
Marmoset brain slices.

Prenatal viral injections prime primate brain for study

The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.

By Angie Voyles Askham
22 January 2026 | 5 min read

privacy consent banner

Privacy Preference

We use cookies to provide you with the best online experience. By clicking “Accept All,” you help us understand how our site is used and enhance its performance. You can change your choice at any time. To learn more, please visit our Privacy Policy.