Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Hands driving a steering wheel with a computer chip.

How, when and why to use agentic AI in our neuroscience labs

With agentic AI’s rapid infiltration into science, researchers need to develop AI use policies and practices.

By Nicolas Schuck
24 August 2026 | 7 min read
Illustration of a coral, sea urchin, snail, and fish.

Climate neuroscience needs ‘integration’ and ‘guided’ research

Five years after a groundbreaking paper, can a young field move beyond piecemeal studies?

By Sarah DeWeerdt
21 August 2026 | 7 min read
Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 4 min read