Dup15q 2017

Recent articles

Mat with pressure sensors detects characteristic gait in dup15q syndrome

People with dup15q syndrome tend to walk slowly, have a wide stance and take short steps.

By Nicholette Zeliadt
31 July 2017 | 5 min read

Anxiety, seizures mark mice with extra copy of autism gene

Mice with an extra copy of UBE3A, a gene linked to autism, have learning problems and anxiety, and are prone to seizures and fine-motor problems.

By Nicholette Zeliadt
31 July 2017 | 4 min read

Antidepressant eases some autism features in mice

A drug that keeps neurons bathed in the chemical messenger serotonin prevents social abnormalities in a mouse model of dup15q syndrome.

By Nicholette Zeliadt
28 July 2017 | 4 min read

Dim light casts shadow on mouse sleep, behavior

Exposure to a dim light at night disrupts sleep and worsens repetitive behaviors and social difficulties in a mouse model of autism.

By Nicholette Zeliadt
28 July 2017 | 3 min read

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Illustration of two researchers attempting to use a microscope that has been twisted into a knot.

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Mother mouse with pups.

Oxytocin shapes both mouse mom and pup behavior

Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.

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Research image showing cell activity in a particular region of the mouse thalamus.

Sensory gatekeeper drives seizures, autism-like behaviors in mouse model

The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.

By Diana Kwon
11 September 2025 | 5 min listen

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