Dup15q 2012

Recent articles

Spectrum from The Transmitter.

Chromosome 15 duplications common in autism

About 1 in 500 children referred to genetic testing for undefined developmental delay, intellectual disability, or autism have duplications of the 15q11-13 chromosomal region, according to a new analysis. That makes the region the second most common large genetic alteration linked to autism.

By Emily Singer
30 August 2012 | 4 min read
Spectrum from The Transmitter.

Researchers eye pigs for modeling autism-related disorder

Researchers plan to develop pig models of Prader-Willi syndrome, an inherited disorder caused by the deletion of an autism-linked region of chromosome 15.

By Emily Singer
13 August 2012 | 2 min read
Spectrum from The Transmitter.

Researchers home in on dosage effects of 15q11-13 region

Researchers are beginning to tease apart how dosage of genes within the 15q11-13 chromosomal region contributes to autism symptoms.

By Emily Singer
13 August 2012 | 5 min read

Explore more from The Transmitter

Autism scientists push back on CDC’s inaccurate vaccine claims

The CDC website now falsely suggests that autism-vaccine research is still an open question, prompting distrust among researchers—some of whom anticipate “more unreliable statements coming from the junta that took over” the agency.

By The Transmitter
21 November 2025 | 6 min read

Gene replacement therapy normalizes some traits in SYNGAP1 model mice

The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.

By Charles Q. Choi
20 November 2025 | 5 min read

Does AI understand what it produces? Henk de Regt explores how we might assess understanding in machines and humans

Building on his philosophy of how scientists understand what they work on, de Regt is extending his approach to test understanding in machines.

By Paul Middlebrooks
19 November 2025 | 1 min read

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