Dopamine

Recent articles

Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Illustration of dopamine neurons.

This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments

In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.

By Talia Lerner
11 March 2026 | 6 min read
Research image of serotonin and dopamine expression in rats.

Sex hormone boosts female rats’ sensitivity to unexpected rewards

During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.

By Angie Voyles Askham
26 November 2025 | 5 min read
Book cover of What Is Intelligence.

‘What Is Intelligence?’: An excerpt

In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.

By Blaise Agüera y Arcas
23 September 2025 | 9 min read
Research image of a mouse brain with the same spot shown three times in different colors to show different neurochemical concentrations.

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 4 min read
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 4 min read
Image of alpha-synuclein filaments in the brain.

Large study links autism to Parkinson’s disease

Autistic adults appear to be prone to an early-onset form of Parkinson’s, according to a long-term study that tracked 2.2 million people in Sweden.

By Charles Q. Choi
5 June 2025 | 4 min read
Research image of a fiber optic implant in a mouse brain.

Bespoke photometry system captures variety of dopamine signals in mice

The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

By Sydney Wyatt
21 March 2025 | 5 min read
Research image of serotonin and dopamine neurons manipulated simultaneously in mice.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning

Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

By Angie Voyles Askham
12 February 2025 | 5 min read
Research image of circuits emerging from striosomes in the striatum.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

By Claudia López Lloreda
24 January 2025 | 4 min read

Explore more from The Transmitter

Illustration of scale balancing Petri dish and test tubes

Every neuroscience lab needs an ethicist

The ethics issues that arise in neuroscience research are usually novel, unresolved and understudied. Embedding ethicists in labs helps scientists navigate these challenges and develop strategies in real time to prevent harm.

By Timothy E. Brown
27 May 2026 | 5 min read
Myelin research image.

Beyond glucose: The brain may feed itself

Myelin may serve as an energy reserve for the brain, according to recent findings, prompting neuroscientists to rethink how the brain stores, shares and protects energy.

By Carlos Matute
26 May 2026 | 6 min read
Research image of genetic models

SHANK3-variant effects in primates, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 25 May.

By Jill Adams
26 May 2026 | 2 min read