Developmental neuroscience
Recent articles
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Waves of calcium activity dictate eye structure in flies
Synchronized signals in non-neuronal retinal cells draw the tiny compartments of a fruit fly’s compound eye into alignment during pupal development.
Waves of calcium activity dictate eye structure in flies
Synchronized signals in non-neuronal retinal cells draw the tiny compartments of a fruit fly’s compound eye into alignment during pupal development.
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Keith Hengen and Woodrow Shew explore criticality and cognition
The two discuss their evolving views of brain criticality as a central organizing principle of cognition, development and learning.
Keith Hengen and Woodrow Shew explore criticality and cognition
The two discuss their evolving views of brain criticality as a central organizing principle of cognition, development and learning.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
How developing neurons simplify their search for a synaptic mate
Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.
Explore more from The Transmitter
Frameshift: Raphe Bernier followed his heart out of academia, then made his way back again
After a clinical research career, an interlude at Apple and four months in early retirement, Raphe Bernier found joy in teaching.
Frameshift: Raphe Bernier followed his heart out of academia, then made his way back again
After a clinical research career, an interlude at Apple and four months in early retirement, Raphe Bernier found joy in teaching.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Single gene sways caregiving circuits, behavior in male mice
Brain levels of the agouti gene determine whether African striped mice are doting fathers—or infanticidal ones.
Single gene sways caregiving circuits, behavior in male mice
Brain levels of the agouti gene determine whether African striped mice are doting fathers—or infanticidal ones.