Circuits

Recent articles

Research figure of fly neurons transforming taste information into movements.

Fly taste connectome traces paths from sensation to action

The map—the first of its kind for an animal more complex than Caenorhabditis elegans—gives neuroscientists a trove of testable hypotheses about how neuronal circuits guide feeding behaviors.

By Lauren Schenkman
30 October 2026 | 5 min read
Headshots of Karl Deisseroth, Peter Hegemann and Georg Nagel.

How Nobel Prize-winning optogenetics has revolutionized neuroscience

The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.

Research diagram of gene expression.

Fly neurons carry molecular signatures of their origins

The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.

By Alissa de Chassey
25 September 2026 | 5 min read

Brainstem neurons add new element to ‘already complex’ anxiety circuitry

Precise optogenetic modulation of a medullary neuron population reveals their role in anxiety-like behaviors.

By Sarah Thau
19 August 2026 | 0 min watch
Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Research images of the mouse visual cortex.

Astrocytes stabilize circuits in adult mouse brain

The glial cells secrete a protein that suppresses plasticity post-development.

By Holly Barker
6 January 2026 | 5 min read
Illustration of human figures holding brightly colored connected dots.

The best of ‘this paper changed my life’ in 2025

From a study that upended astrocyte research to one that reignited the field of spiking neural networks, experts weighed in on the papers that significantly shaped how they think about and approach neuroscience.

By The Transmitter
24 December 2025 | 2 min read
Archery target.

What should the field prioritize over the next 10 years?

Respondents pointed to a range of challenges in basic neuroscience—such as understanding naturalistic behaviors, intelligence and embodied cognition—and called for more circuit-level research, more precise brain recordings and more work in alternative models. Just as many pushed for a translational pivot.

By The Transmitter
15 November 2025 | 11 min read
Illustration of a fly in various poses.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

By Bradley Dickerson
17 June 2025 | 5 min read
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 6 min read

Explore more from The Transmitter

Brain registers spatial location outside hippocampus

A more complex picture of how an animal’s brain tracks its location is starting to emerge.

By Natalia Mesa
5 November 2026 | 1 min watch
Illustration of worm on top of a purple rock with neurons in the background.

The three-banded panther worm is rewriting the story of brain evolution

The animal has a brain structure all its own, according to a 2026 preprint. The finding hints that brains could have evolved centralization before regionalization.

By Sarah DeWeerdt
4 November 2026 | 7 min read

Does cognition happen in brain areas or between them?

Michael Cole explains how "brain flows" are the fundamental units of brain function and cognition.

By Paul Middlebrooks
4 November 2026 | 1 min read