Circuits

Recent articles

A cortical neuron glows orange and red.

START method assembles brain’s wiring diagram by cell type

The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

By Holly Barker
31 October 2024 | 5 min read
Research image of neurons in the nucleus of the mouse solitary tract.

Cell population in brainstem coordinates cough, new study shows

The work also adds to a growing body of evidence showing that mice, and their genetic toolbox, can be used to study cough.

By Calli McMurray
6 September 2024 | 5 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Research image of neurons in the rostral anterior cingulate cortex (right, in green) sending signals to cells in the pontine nucleus (left, in yellow) to quell pain.

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read
Research image of a variety of brain atlases.

New ‘decoder’ tool translates functional neuroimaging terms across labs

The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

By Holly Barker
23 July 2024 | 4 min read

Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’

Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.

By Angie Voyles Askham
17 May 2024 | 5 min read
A diagram of green neurnons

Cocaine, morphine commandeer neurons normally activated by food, water in mice

Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

By Lauren Schenkman
8 May 2024 | 5 min read
A flourescent blue and green brain picture

New genetic tools usher amphibian neuroscience research into modern age

Harmless viruses that ferry genes into the brain cells of rodents and monkeys also work in frogs, newts and axolotls, according to two new preprints.

By Angie Voyles Askham
23 April 2024 | 6 min read

Drafting a ‘dysfunctome’: Faulty connections to subthalamic nucleus characterize disparate brain disorders

Different circuits between the millimeters-wide structure and the cortex go awry in Tourette syndrome, obsessive-compulsive disorder, dystonia and Parkinson’s disease, a new study of human brain scans suggests.

By Elissa Welle
16 April 2024 | 5 min read

Explore more from The Transmitter

Research image of a portion of mouse brain.

Stress warps fear memories in multiple ways

Expanding the bounds of a fear memory or linking it to a neutral memory can shape a mouse’s fear response, two new studies show.

By Claudia López Lloreda
15 November 2024 | 5 min read
Illustration of overlapping silhouettes of two faces in profile facing a matrix of dots of various colors and sizes.

How to be a multidisciplinary neuroscientist

Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.

By Austin Coley
15 November 2024 | 5 min read
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read