Calcium imaging

Recent articles

Detailed image of neurons in the mouse visual cortex.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain

A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

By Katie Moisse
9 April 2025 | 6 min read
Raphael Yuste leaning on a bench in his lab. A red filter colors the scene.

Releasing the Hydra with Rafael Yuste

Losing HHMI Investigator status prompted Yuste to study neural networks in a new way.

By Brady Huggett, Shaena Montanari
4 April 2025 | 10 min read
Research image of mouse cells.

Immune cell interlopers breach—and repair—brain barrier in mice

The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

By Claudia López Lloreda
20 November 2024 | 6 min listen

New tissue-clearing techniques let microscopes peer deeper into living brains

Washing mouse brain tissue with a blood protein or complex sugar can illuminate cells 550 micrometers into the cortex without compromising its normal physiology.

By Calli McMurray
18 October 2024 | 0 min watch
Illustrated portrait of Lin Tian.

Biosensors and being fearless with Lin Tian

Tian discusses protein function and structure, and the historic city in China where she was born.

By Brady Huggett
1 September 2024 | 62 min listen

Widely used calcium imaging protocol can lead to spurious results, new paper cautions

The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.

By Angie Voyles Askham
19 June 2024 | 0 min watch
A research image of a mouse with a device attached to its head

Innovative device records activity from distant brain areas simultaneously

The headset combines calcium imaging and electrode recordings to track both the cerebellum and anterior cingulate cortex as mice socialize.

By Claudia López Lloreda
4 April 2024 | 4 min read

Explore more from The Transmitter

Research image of resting-state functional activity in a human brain.

Developmental delay patterns differ with diagnosis; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 14 April.

By Jill Adams
15 April 2025 | 2 min read
Illustration of a treeline in front of a human brain.

‘Natural Neuroscience: Toward a Systems Neuroscience of Natural Behaviors,’ an excerpt

In his new book, published today, Nachum Ulanovsky calls on the field to embrace naturalistic conditions and move away from overcontrolled experiments.

By Nachum Ulanovsky
15 April 2025 | 9 min read
Close-up of high-resolution fMRI images.

Functional MRI can do more than you think

Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.

By Laura Lewis
14 April 2025 | 6 min read