BTBR mice

Recent articles

Artificial intelligence system categorizes interactions between mice

New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.

By Lauren Schenkman
17 December 2021 | 4 min read

New mouse brain atlas traces connections in fine detail

A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.

By Laura Dattaro
13 January 2021 | 2 min read
illustration of mouse on sale in a city

‘Outmoded’ mouse models of autism may still yield new advances

Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.

By Nicholette Zeliadt
21 March 2018 | 6 min read
Spectrum from The Transmitter.

Mouse studies support second chance for fragile X drug

Two new studies give a boost to arbaclofen, which failed to meet expectations in clinical trials for autism and fragile X syndrome.

By Jessica Wright
28 April 2015 | 3 min read
Spectrum from The Transmitter.

Optimizing behavioral assays for mouse models of autism

As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.

By Jacqueline Crawley
23 September 2014 | 11 min read
Spectrum from The Transmitter.

Signaling imbalance skews sensory responses in autism mice

Mice modeling autism have trouble integrating different kinds of sensory information such as sight, sound and touch. A study published 31 July in Neuron reports that an imbalance between signals that calm neurons and those that excite them leads to these sensory problems.

By Maris Fessenden
11 August 2014 | 5 min read
Spectrum from The Transmitter.

Low-dose sedative eases autism symptoms in mice

The equivalent of one-tenth of a single pill of the anxiety drug clonazepam alleviates many autism-like behaviors in a mouse model of the disorder, according to a study published 19 March in Neuron.

By Jessica Wright
3 April 2014 | 5 min read
Spectrum from The Transmitter.

Automated tool records behavior of autism mouse models

A new tracking system automatically logs and scores mouse behavior as well as a human observer does, according to a paper published 31 December 2013 in Journal of Neuroscience Methods.

By Veronique Greenwood
5 February 2014 | 3 min read
Spectrum from The Transmitter.

Cognition and behavior: Drug ups sociability in autism mice

Rapamycin, a drug given to suppress immune rejection after transplants, improves social behavior in mice with features of autism, reports a study published in the January issue of Brain Research Bulletin.

By Laura Geggel
31 January 2014 | 2 min read
Spectrum from The Transmitter.

Compendium of mouse brains highlights autism’s diversity

By mapping the brains of not 1 but 27 mouse models of autism, researchers are making sense of the widely divergent structural changes seen in autism brains, they reported Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.

By Jessica Wright
14 November 2013 | 4 min read

Explore more from The Transmitter

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read