Biomarkers
Recent articles
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.

Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.

Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
Data access changes to UK Biobank stir unease in neuroscientists
“I feel a little bit in limbo,” says neuroscientist Stephanie Noble, who has paused a study using Biobank data after the repository shifted from a data download to a cloud-only access model.

Data access changes to UK Biobank stir unease in neuroscientists
“I feel a little bit in limbo,” says neuroscientist Stephanie Noble, who has paused a study using Biobank data after the repository shifted from a data download to a cloud-only access model.
Crowdsourcing to curb aggression in autism: Q&A with Matthew Goodwin
To accelerate the development of real-time behavioral prediction technology, a research team is sharing data and seeking new collaborators.

Crowdsourcing to curb aggression in autism: Q&A with Matthew Goodwin
To accelerate the development of real-time behavioral prediction technology, a research team is sharing data and seeking new collaborators.
Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.
Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.

Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
New tablet-based tools to spot autism draw excitement — and questions
Handheld devices promise to bring autism detection home, but many researchers urge caution.

New tablet-based tools to spot autism draw excitement — and questions
Handheld devices promise to bring autism detection home, but many researchers urge caution.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Looking at eye tracking’s potential for clinical trials
This month’s Going on Trial newsletter explores how eye tracking might be used beyond helping with diagnosis, among other drug development news.

Looking at eye tracking’s potential for clinical trials
This month’s Going on Trial newsletter explores how eye tracking might be used beyond helping with diagnosis, among other drug development news.
Explore more from The Transmitter
Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.

Newly awarded NIH grants for neuroscience lag 77 percent behind previous nine-year average
Since President Donald Trump took office on 20 January, the National Institute of Neurological Disease and Stroke and the National Institute of Mental Health have awarded one quarter as many new grants as during the same two-month period, on average, since 2016.
Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.

Releasing the Hydra with Rafael Yuste
Losing HHMI Investigator status caused Yuste to study neural networks in a new way.
Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.

Coding error caused layoffs at National Institute of Neurological Disorders and Stroke this week, source says
Thirty employees—including 11 lab heads—at the institute should “immediately return to work,” according to an email the institute’s Office of Human Resources sent to top administration at the institute Wednesday evening.