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Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.
![Research image of gene expression in cells in the third ventricle of the hypothalamus of young and aged mice.](https://www.thetransmitter.org/wp-content/uploads/2025/01/1200-cell-specific-aging-transmitter-neuroscience-1024x683.png)
Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.
Males and females show different patterns of risk for brain-based conditions. Ignoring these differences does us all a disservice.
Although studying sex differences in the brain is complex, technically awkward and socioculturally loaded, it is absolutely essential.
![Illustration of men’s and women’s faces.](https://www.thetransmitter.org/wp-content/uploads/2024/12/Raznahan-Sex-Differences-neuro-1200-1024x692.png)
Males and females show different patterns of risk for brain-based conditions. Ignoring these differences does us all a disservice.
Although studying sex differences in the brain is complex, technically awkward and socioculturally loaded, it is absolutely essential.
Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.
![Research image of mouse cells.](https://www.thetransmitter.org/wp-content/uploads/2024/11/1200-neuroscience-transmitter-choroid-plexus-immune-organ-1024x683.png)
Immune cell interlopers breach—and repair—brain barrier in mice
The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.
NeuroAI: A field born from the symbiosis between neuroscience, AI
As the history of this nascent discipline reveals, neuroscience has inspired advances in artificial intelligence, and AI has provided a testing ground for models in neuroscience, accelerating progress in both fields.
![Illustration of a brain overlaid with circles containing flowers and circuit-like networks, among other images.](https://www.thetransmitter.org/wp-content/uploads/2024/11/ai-history-neuro-Zador-1200-1024x692.webp)
NeuroAI: A field born from the symbiosis between neuroscience, AI
As the history of this nascent discipline reveals, neuroscience has inspired advances in artificial intelligence, and AI has provided a testing ground for models in neuroscience, accelerating progress in both fields.
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
![Research image of fMRI scans on a black background.](https://www.thetransmitter.org/wp-content/uploads/2024/10/1200-stimulus-steady-state-1024x683.webp)
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
![A collage illustration of a woman’s face fragmented by a mosaic of X chromosomes, lines and shapes.](https://www.thetransmitter.org/wp-content/uploads/2024/10/Buckely-SexDifferences-neuro-1200-1024x683.webp)
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
This paper changed my life: ‘Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,’ from the Fiser Lab
Fiser’s work taught me how to think about grounding computational models in biologically plausible implementations.
![Illustration of three columns of text with certain passages underlined and circled.](https://www.thetransmitter.org/wp-content/uploads/2024/10/1200-this-paper-changed-my-life-fiser-1024x683.webp)
This paper changed my life: ‘Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,’ from the Fiser Lab
Fiser’s work taught me how to think about grounding computational models in biologically plausible implementations.
The S-index Challenge: Develop a metric to quantify data-sharing success
The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.
![Illustration of three figures standing in front of a grid of dots and a world map.](https://www.thetransmitter.org/wp-content/uploads/2024/10/1200-frank-s-index-transmitter-neuroscience-1-1024x692.webp)
The S-index Challenge: Develop a metric to quantify data-sharing success
The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.
A scientific fraud. An investigation. A lab in recovery.
Science is built on trust. What happens when someone destroys it?
![Illustration of a lab with a smoking crater in the middle of the floor.](https://www.thetransmitter.org/wp-content/uploads/2024/10/tt-neuroscience-lab-investigation-fraud-retraction-inside-lede-1200-1024x683.webp)
A scientific fraud. An investigation. A lab in recovery.
Science is built on trust. What happens when someone destroys it?
Repeat scans reveal brain changes that precede childbirth
A detailed look at a “pregnant brain” highlights a need to investigate the neural alterations that occur during a transition experienced by nearly 140 million people worldwide each year.
![Research image of brain scans showing the structural integrity of white-matter tracts.](https://www.thetransmitter.org/wp-content/uploads/2024/09/White-matter-pregnancy-neuroscience-LEDE-1200-1024x692.png)
Repeat scans reveal brain changes that precede childbirth
A detailed look at a “pregnant brain” highlights a need to investigate the neural alterations that occur during a transition experienced by nearly 140 million people worldwide each year.
Explore more from The Transmitter
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
![Illustration of a body, brain visible through a transparent head, looking at orange circles over its hands.](https://www.thetransmitter.org/wp-content/uploads/2025/02/1200-hodes-body-brain-mental-health-neuroscience-1024x683.png)
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
How eight initiatives are tackling neuroscience’s gender gap
In honor of today’s International Day of Women and Girls in Science, The Transmitter spoke with some of the women working to bolster their ranks in the field through storytelling podcasts, speaker repositories, social media networks and other community-based advocacy projects.
![Illustrated collage of women doing scientific tasks: looking at brain slices, pouring a solution into a beaker and looking into a microscope.](https://www.thetransmitter.org/wp-content/uploads/2025/02/1200-women-neuroscience-gender-imbalance-1024x683.png)
How eight initiatives are tackling neuroscience’s gender gap
In honor of today’s International Day of Women and Girls in Science, The Transmitter spoke with some of the women working to bolster their ranks in the field through storytelling podcasts, speaker repositories, social media networks and other community-based advocacy projects.
TSC2 gene; cortical thickness; long noncoding RNA
Here is a roundup of autism-related news and research spotted around the web for the week of 10 February.
![Research image of neural rosettes.](https://www.thetransmitter.org/wp-content/uploads/2025/02/1200-spotted-TSC2-RNA-autism-1024x683.png)
TSC2 gene; cortical thickness; long noncoding RNA
Here is a roundup of autism-related news and research spotted around the web for the week of 10 February.