ASHG 2019

Recent articles

RNA, transcription

Antidote to ‘poison’ DNA may treat lethal form of epilepsy

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

By Nicholette Zeliadt
26 August 2020 | 3 min read

Brain ‘organoids’ point to new drug target for fragile X syndrome

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

By Nicholette Zeliadt
18 October 2019 | 3 min read
Illustration of a DNA strand.

Massive project doubles list of genes tied to autism

The largest analysis of sequences from autistic people and their families implicates 184 genes in the condition — nearly doubling the previous estimate.

By Nicholette Zeliadt
17 October 2019 | 3 min read

Explore more from The Transmitter

Illustration of a shrew, sandpiper, locust, axolotl, monarch butterfly, African killifish, naked mole rat, octopus, bat and cichlid.

The non-model organism “renaissance” has arrived

Meet 10 neuroscientists bringing model diversity back with the funky animals they study.

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
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Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence

Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.

By Paul Middlebrooks
18 December 2024 | 97 min listen