ASHG 2015

Recent articles

Spectrum from The Transmitter.

Analysis makes sense of missense mutations’ role in autism

Analyzing thousands of sequences, researchers have homed in on miniscule portions of the genome that may be crucial in determining autism risk.

By Jessica Wright
12 October 2015 | 6 min read
Spectrum from The Transmitter.

New methods tighten ​net​ around autism genes

Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.

By Jessica Wright
9 October 2015 | 4 min read
Spectrum from The Transmitter.

Dispatches from ASHG 2015

These short reports from our reporter, Jessica Wright, give you the inside scoop on developments at the 2015 American Society of Human Genetics Annual Meeting.

By Jessica Wright
9 October 2015 | 6 min read
Spectrum from The Transmitter.

Twin study unearths clues to role of environment in autism

Researchers in Sweden are assembling a large group of identical twin pairs, with only one twin in each pair having autism.

By Jessica Wright
8 October 2015 | 4 min read

Explore more from The Transmitter

Pixelated human brain scans showing the distribution of mitochondria.

Mitochondrial ‘landscape’ shifts across human brain

Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

By Claudia López Lloreda
25 April 2025 | 6 min read
A clinician holds a clipboard while someone else sits on a couch.

Expediting clinical trials for profound autism: Q&A with Matthew State

Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

By Lauren Schenkman
24 April 2025 | 8 min read
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 6 min read